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Home/Compounds/Pharmaceutical Intermediate/N-Cbz-N'-Boc-L-lysine
C19H28N2O6
380.4 g/mol
Pharmaceutical Intermediate

IN2-(benzyloxycarbonyl)-N6-(tert-butoxycarbonyl)-L-lysine

CAS2389-60-8EC219-223-1
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid derivative used in peptide synthesis. It features both a benzyloxycarbonyl (Cbz) group and a tert-butoxycarbonyl (Boc) protecting group on the lysine side chain, allowing selective deprotection during solid-phase or solution-phase peptide assembly.

Intermediate for solid-phase peptide synthesisBuilding block for pharmaceutical research compoundsProtected lysine derivative for custom peptide production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.91

N-Boc-N'-Cbz-L-lysine

CAS2389-45-9

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StrongStructure SimilarSimilarity 0.85

N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine

CAS2480-93-5

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.85

N-Cbz-N'-Boc-L-2,4-Diaminobutyric acid dicyclohexylamine salt

CAS3350-13-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

N,N'-Dibenzyloxycarbonyl-L-lysine

CAS405-39-0

pharmaceutical intermediate

ApplicationSame Use

N-Cbz-L-Phenylalanine

CAS1161-13-3

pharmaceutical intermediate

ApplicationSame Use

Fmoc-O-tert-butyl-D-tyrosine

CAS118488-18-9

pharmaceutical intermediate

ApplicationSame Use

Boc-L-Glutamine

CAS13726-85-7

pharmaceutical intermediate

ApplicationSame Use

N-Boc-L-Lysine

CAS13734-28-6

pharmaceutical intermediate

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Customs Tariff Classification

The international HS code for IN2-(benzyloxycarbonyl)-N6-(tert-butoxycarbonyl)-L-lysine (CAS 2389-60-8) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)hexanoic acid

InChIKey

DYSBKEOCHROEGX-HNNXBMFYSA-N

SMILES

CC(C)(C)OC(=O)NCCCC[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1

Synonyms (22)
  • CBZ-LYS(BOC)-OH
  • Cbz-L-Lys(Boc)-OH
  • Lysine derivative 1
  • N-Cbz-N'-Boc-L-lysine
  • N6-Boc-N2-Cbz-D-lysine
  • N6-Boc-N2-Cbz-L-lysine
  • Z-L-LYS(BOC)-OH
  • Z-Lys(Boc)
  • Z-Lys(Boc)-OH

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