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Home/Compounds/Pharmaceutical Intermediate/N-Boc-N'-Cbz-L-lysine
C19H28N2O6
380.4 g/mol
Pharmaceutical IntermediateWarning

Boc-Lys(Z)-OH

CAS2389-45-9EC219-221-0
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected derivative of the amino acid lysine, featuring both Boc (tert-butyloxycarbonyl) and Cbz (benzyloxycarbonyl) protecting groups. It is primarily used as a building block in peptide synthesis, enabling the selective incorporation of lysine residues into peptide chains during laboratory and manufacturing processes.

Protected amino acid reagent for solid-phase peptide synthesisIntermediate in the production of custom peptides for researchBuilding block for manufacturing pharmaceutical peptide intermediates

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.93

N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine

CAS2480-93-5

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.91

N-Cbz-N'-Boc-L-lysine

CAS2389-60-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

N,N'-Dibenzyloxycarbonyl-L-lysine

CAS405-39-0

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.78

N-Cbz-N'-Boc-L-2,4-Diaminobutyric acid dicyclohexylamine salt

CAS3350-13-8

pharmaceutical intermediate

ApplicationSame Use

Boc-L-Serine

CAS3262-72-4

pharmaceutical intermediate

ApplicationSame Use

N-Boc-N'-trityl-L-histidine

CAS32926-43-5

pharmaceutical intermediate

ApplicationSame Use

Fmoc-D-Lys(Dde)-OH

CAS333973-51-6

pharmaceutical intermediate

ApplicationSame Use

Alloc-Lys(Fmoc)-OH

CAS186350-56-1

pharmaceutical intermediate

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Boc-Lys(Z)-OH (CAS 2389-45-9) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-(phenylmethoxycarbonylamino)hexanoic acid

InChIKey

BDHUTRNYBGWPBL-HNNXBMFYSA-N

SMILES

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCC1=CC=CC=C1)C(=O)O

Synonyms (29)
  • BOC-L-LYS(CBZ)-OH
  • BOC-L-Lys(Z)
  • BOC-LYS(CBZ)-OH
  • Boc-L-Lys(Z)-OH
  • Boc-Lys(Z)-OH
  • n-boc-n'-cbz-l-lysine

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