C30H31N3O4
497.6 g/mol
Pharmaceutical IntermediateWarning
Boc-His(Trt)-OH, Nalpha-Boc-N(im)-trityl-L-histidine
CAS32926-43-5EC685-644-6
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
Boc-His(1-Trt)-OH is a protected amino acid derivative used as a building block in peptide synthesis. Its structure includes a tert-butoxycarbonyl (Boc) protecting group on the amino function and a trityl (Trt) group on the imidazole side chain of histidine, enabling selective deprotection during solid-phase peptide assembly.
protected amino acid for peptide synthesispharmaceutical intermediate
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 32926-43-5
Related Compounds
SimilarStructure SimilarSimilarity 0.80
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(1-tritylimidazol-4-yl)propanoic acid
InChIKey
OYXZPXVCRAAKCM-SANMLTNESA-N
SMILES
CC(C)(C)OC(=O)N[C@@H](CC1=CN(C=N1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)O
Synonyms (15)
- (S)-L-Boc-His(Trt)-OH
- Boc-His(Trt)-OH