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Home/Compounds/Pharmaceutical Intermediate/Fmoc-O-tert-butyl-D-tyrosine
C28H29NO5
459.5 g/mol
Pharmaceutical IntermediateWarning

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid

CAS118488-18-9EC813-028-0
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid derivative used as an intermediate in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino terminus and a tert-butyl ether protecting group on the tyrosine side chain, enabling selective deprotection during solid-phase peptide assembly.

Protected amino acid for peptide synthesisBuilding block in solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine

CAS181951-92-8

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SimilarStructure SimilarSimilarity 0.73

Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine

CAS1013883-02-7

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ApplicationSame Use

Boc-L-Glutamine

CAS13726-85-7

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ApplicationSame Use

N-Boc-L-Lysine

CAS13734-28-6

pharmaceutical intermediate

ApplicationSame Use

Boc-O-Benzyl-L-threonine

CAS15260-10-3

pharmaceutical intermediate

ApplicationSame Use

N-(tert-Butoxycarbonyl)-L-alanine

CAS15761-38-3

pharmaceutical intermediate

ReferenceSame Category

N-(2-Chloro-4-methyl-3-pyridinyl)-2-(cyclopropyl-d5-amino)-3-pyridine-carboxamide

CAS1184978-88-8

pharmaceutical intermediate

ReferenceSame Category

Tromethamine hydrochloride

CAS1185-53-1

pharmaceutical intermediate

Related Reading

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Safety Reference

Harmful
Harmful
Environmental Hazard
Environmental Hazard
Warning
H317May cause an allergic skin reaction
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid

InChIKey

JAUKCFULLJFBFN-RUZDIDTESA-N

SMILES

CC(C)(C)OC1=CC=C(C=C1)C[C@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Synonyms (16)
  • Fmoc-D-Tyr(tBu)-OH
  • Fmoc-O-tert-butyl-D-tyrosine

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