C4H12ClNO3
157.59 g/mol
Pharmaceutical IntermediateWarning
Tris hydrochloride
CAS1185-53-1EC214-684-5
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
Tris hydrochloride is a common buffer compound and pharmaceutical intermediate. It is typically used in biochemical and molecular biology applications as a buffering agent.
Buffer in biochemical researchPharmaceutical intermediate
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Tris acetate
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StrongSame Parent
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Oxalic acid--2-amino-2-(hydroxymethyl)propane-1,3-diol (1/1)
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Tris hydrochloride (CAS 1185-53-1) is 2922.19.
HS code (international, 6-digit)
2922.19
EU CN code (8-digit)
2922 19 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChIKey
QKNYBSVHEMOAJP-UHFFFAOYSA-N
SMILES
C(C(CO)(CO)N)O.Cl
Synonyms (44)
- 1185-53-1 (solid)
- THAM hydrochloride
- TRIS HCl
- Tris HCl, biochemical grade
- Tris chloride
- Tris hydrochloric acid
- Tris hydrochloride
- Tris hydrochloride buffer
- Trizma hydrochloride
- Trizma(R) hydrochloride
- Trometamol HCl
- Trometamol hydrochloride
- Tromethamine HCl
- Tromethamine hydrochloride
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