C4H11NO3
121.14 g/mol
APIWarning
Trometamol
CAS77-86-1EC201-064-4
Category
API
Compound Class
Alcohol
Primary Use
Pharmaceutical Raw Material
Trometamol (tromethamine) is an alkalinizing active pharmaceutical ingredient used primarily as a buffer in pharmaceutical manufacturing. Its structure features multiple hydroxyl groups and an amine, contributing to its high polarity and water solubility.
alkalinizing agent in pharmaceutical formulationsindustrial use in leather tanning and textile processing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Fosfomycin tromethamine
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pharmaceutical raw material
StrongSame Parent
Oxalic acid--2-amino-2-(hydroxymethyl)propane-1,3-diol (1/1)
CAS855392-18-6
pharmaceutical intermediate
StrongSame Parent
Tromethamine hydrochloride
CAS1185-53-1
pharmaceutical intermediate
StrongSame Parent
Tris acetate
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research compound
ReferenceSame Category
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CAS770-05-8
pharmaceutical raw material
ReferenceSame Category
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pharmaceutical raw material
ReferenceSame Category
Hypocrellin a
CAS77029-83-5
pharmaceutical raw material
ReferenceSame Category
Erythromycin thiocyanate
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pharmaceutical raw material
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Trometamol (CAS 77-86-1) is 2922.19.
HS code (international, 6-digit)
2922.19
EU CN code (8-digit)
2922 19 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-amino-2-(hydroxymethyl)propane-1,3-diol
InChIKey
LENZDBCJOHFCAS-UHFFFAOYSA-N
SMILES
C(C(CO)(CO)N)O
Synonyms (85)
- THAM-E
- TRS
- Trizma(R) base, BioPerformance Certified, meets EP, USP testing specifications, cell culture tested, >=99.9% (titration)
- Trometamol (JAN/INN)
- Trometamol, European Pharmacopoeia (EP)
- Trometamolum [INN-Latin]
- Tromethamine (USP)
- Tromethamine, United States Pharmacopeia (USP)
- Tromethamine, meets USP testing specifications
- 1, 2-amino-2-(hydroxymethyl)-
- 1gng
- 1h4n
- ABX (ANTIBODY EXCHANGER)
- Addex-tham
- Aminotrimethylolmethane
- Pehanorm
- THAM (Standard)
- THAM (TN)
- THAM, >/=99.5%
- THAM-E COMPONENT TROMETHAMINE
- TROMETAMOL [MART.]
- Talatrol
- Tham
- Trigmo base
- Triladyl
- Trimethylolaminomethane
- Tris
- Tris (buffering agent)
- Tris Amino
- Tris Borat EDTA buffer soln
- Tris buffer
- Tris, free base
- Tris-Mg(II)-KCl Buffer
- Tris-base
- Tris-steril
- Trisamin
- Trisamine
- Trisaminol
- Trispuffer
- Trizma
- Trizma base
- Trizma(R) base, >=99.0% (T)
- Trometamol
- Trometamol CRS
- Trometamole
- Trometamolum
- Tromethamin
- Tromethamine
- Tromethamolum
- Tromethane
- Tromethanmin
- Tutofusin tris
- bakerbond(tm) cyano (cn)
- tris base solution
- trometamolo
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