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Home/Compounds/Pharmaceutical Intermediate/(S)-2-Fmoc-aminohexanedioic acid 6-tert-butyl ester
C25H29NO6
439.5 g/mol
Pharmaceutical Intermediate

Fmoc-Aad(otBu)-OH

CAS159751-47-0
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Fmoc-Aad(otBu)-OH is a protected amino acid derivative used in solid-phase peptide synthesis. Its structure includes a fluorenylmethoxycarbonyl (Fmoc) protecting group and a tert-butyl ester on the side chain, enabling selective deprotection during peptide assembly.

Protected building block for peptide synthesisReagent for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.88

Fmoc-L-Glutamic acid-O-tert-butyl ester hydrate

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StrongStructure SimilarSimilarity 0.88

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StrongStructure SimilarSimilarity 0.88

Fmoc-D-glutamic acid gamma-tert-butyl ester

CAS104091-08-9

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SimilarStructure SimilarSimilarity 0.77

Fmoc-D-Aspartic acid beta-tert-butyl ester

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ReferenceSame Category

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ReferenceSame Category

(E)-2-cyano-3-morpholinoacrylamide

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ReferenceSame Category

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(4-methoxyphenyl)diphenylmethyl]-L-lysine

CAS159857-60-0

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ReferenceSame Category

(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide

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Identifiers
IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid

InChIKey

FFLAQPKWVSSKJC-NRFANRHFSA-N

SMILES

CC(C)(C)OC(=O)CCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms (17)
  • Fmoc-Aad(otBu)-OH
  • Fmoc-L-Aad(OtBu)-OH
  • Fmoc-hGlu(OtBu)-OH
  • FmocAad(tBu)OH

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