C24H27NO6
425.5 g/mol
Pharmaceutical IntermediateWarning
(2R)-5-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid
CAS104091-08-9EC860-518-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a protected derivative of D-glutamic acid, featuring an Fmoc group for temporary amine protection and tert-butyl ester groups for side-chain carboxyl protection. It is primarily employed as a building block in solid-phase peptide synthesis to introduce the D-glutamic acid residue.
Fmoc-based solid-phase peptide synthesisPreparation of D-glutamic acid-containing peptides
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 104091-08-9
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StrongStructure SimilarSimilarity 0.88
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
InChIKey
OTKXCALUHMPIGM-HXUWFJFHSA-N
SMILES
CC(C)(C)OC(=O)CC[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (19)
- Fmoc CD-Glu(Otbu)-Oh
- Fmoc-D-Glu(OtBu)-OH
- Fmoc-D-Glu(OtBu)-OH H
- Fmoc-D-Glu(OtBu)-OH.H2O
- Fmoc-D-Glu(OtBu)-OH.nH2O
- Fmoc-D-glu(t-bu)-OH