Home/Compounds/Pharmaceutical Intermediate/(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide
C18H29N5O4
379.5 g/mol
Pharmaceutical IntermediateWarning
(2S)-5-((aminocarbonyl)amino)-2-(((2S)-2-amino-3-methylbutanoyl)amino)-N-(4-(hydroxymethyl)phenyl)pentanamide
CAS159857-79-1EC826-617-2
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a chiral peptide derivative used as a linker intermediate in the production of antibody-drug conjugates (ADCs). Its structure includes amine, amide, and alcohol functional groups, contributing to its role in forming stable conjugates.
Antibody-drug conjugate linker intermediatePharmaceutical intermediate for targeted therapy research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 159857-79-1
Related Compounds
ReferenceSame Category
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
CAS159857-80-4
pharmaceutical intermediate
ReferenceSame Category
(S)-2-((S)-2-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-3-METHYLBUTANAMIDO)-5-UREIDOPENTANOIC ACID
CAS159858-21-6
pharmaceutical intermediate
ReferenceSame Category
High School DxD
CAS1599440-33-1
pharmaceutical intermediate
ReferenceSame Category
(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
CAS159991-23-8
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide
InChIKey
VEGGTWZUZGZKHY-GJZGRUSLSA-N
SMILES
CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N
Synonyms (12)
- Val-Cit-PAB
- Val-cit-PAB-OH
- Val-cit-PAB-OH (GMP)