ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/High School DxD
C26H24FN3O6
493.5 g/mol
Pharmaceutical Intermediate

Dxd

CAS1599440-33-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

Dxd is a pharmaceutical intermediate used in the synthesis of antibody-drug conjugates. It is a derivative of exatecan, a topoisomerase I inhibitor, and serves as the cytotoxic payload in targeted cancer therapies.

industrial reagent for the manufacturing of antibody-drug conjugatesresearch compound in the development of targeted cancer therapeuticspharmaceutical intermediate for exatecan-based ADC production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 1599440-33-1

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

SimilarStructure SimilarSimilarity 0.76

Exatecan mesylate

CAS169869-90-3

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.76

Exatecan

CAS171335-80-1

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.76

Exatecan hydrochloride

CAS144008-87-7

pharmaceutical raw material

ReferenceSame Category

(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid

CAS159991-23-8

pharmaceutical intermediate

ReferenceSame Category

MC-GGFG-Exatecan

CAS1600418-29-8

pharmaceutical intermediate

ReferenceSame Category

7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

CAS160129-45-3

pharmaceutical intermediate

ReferenceSame Category

2,6-dichloro-3-nitropyridine

CAS16013-85-7

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide

InChIKey

PLXLYXLUCNZSAA-QLXKLKPCSA-N

SMILES

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)CO)O

Synonyms (4)
  • Dxd
  • Exatecan derivative for ADC