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Home/Compounds/Pharmaceutical Intermediate/MC-GGFG-Exatecan
C49H51FN8O11
947 g/mol
Pharmaceutical Intermediate

MC-GGFG-Exatecan

CAS1600418-29-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

MC-GGFG-Exatecan is a pharmaceutical intermediate used as an antibody-drug conjugate (ADC) linker payload. It combines a maleimide-containing linker (MC) with a tetrapeptide (GGFG) and the cytotoxic agent exatecan, enabling targeted drug delivery in research settings.

antibody-drug conjugate linker payloadresearch compound for targeted drug delivery studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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StrongStructure SimilarSimilarity 0.91

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Identifiers
IUPAC Name

6-(2,5-dioxopyrrol-1-yl)-N-[2-[[2-[[(2S)-1-[[2-[[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide

InChIKey

XEKFDUNPKACYAY-SODISJPWSA-N

SMILES

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)CNC(=O)[C@H](CC7=CC=CC=C7)NC(=O)CNC(=O)CNC(=O)CCCCCN8C(=O)C=CC8=O)O

Synonyms (4)
  • MC-GGFG-DX8951?
  • MC-GGFG-Exatecan
  • Trastuzumab Impurity 1