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Home/Compounds/API/2H-Pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4S,12aR)-
C20H19F2N3O5
419.4 g/mol
API

Dolutegravir S,R

CAS1309560-49-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Dolutegravir S,R is a stereochemically defined pharmaceutical active ingredient used in the manufacturing of antiretroviral therapies. It is characterized by a complex polycyclic structure containing multiple ring systems and functional groups typical of integrase inhibitor compounds.

Pharmaceutical raw material for integrase inhibitor drug productsStereochemical reference standard for quality control in drug manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

4-Defluoro dolutegravir

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3'-Hydroxypropiophenone

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Referencestereoisomer of

4-epi-Dolutegravir

CAS1357289-29-2

pharmaceutical raw material

Referencestereoisomer of

Dolutegravir

CAS1051375-16-6

pharmaceutical raw material

Referencestereoisomer of

Dolutegravir sodium

CAS1051375-19-9

pharmaceutical raw material

Identifiers
IUPAC Name

(3R,7S)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide

InChIKey

RHWKPHLQXYSBKR-ZUZCIYMTSA-N

SMILES

C[C@H]1CCO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O

Synonyms (4)
  • Dolutegravir Impurity 2
  • Dolutegravir SR Isomer
  • dolutegravir S,R