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Home/Compounds/API/Dolutegravir
C20H19F2N3O5
419.4 g/mol
APIWarning

Dolutegravir

CAS1051375-16-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Dolutegravir is an antiretroviral compound used as an HIV-1 integrase inhibitor. It serves as a pharmaceutical raw material in the manufacturing of medications for HIV/AIDS treatment and prevention.

Pharmaceutical manufacturing for HIV treatmentActive pharmaceutical ingredient in integrase inhibitor formulations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

4-Defluoro dolutegravir

CAS1863916-87-3

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

(4R,12aS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide

CAS1335210-35-9

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.74

Dolutegravir o-benzyl impurity

CAS1206102-11-5

pharmaceutical raw material

ApplicationSame Use

Bictegravir sodium

CAS1807988-02-8

pharmaceutical raw material

ReferenceSame Category

7-methyl-2-(2,2,3,3-tetradeuteriocyclopropyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one

CAS1051418-95-1

pharmaceutical raw material

ReferenceSame Category

Tetrabutylammonium acetate

CAS10534-59-5

pharmaceutical raw material

ReferenceSame Category

Ne-58018

CAS105462-23-5

pharmaceutical raw material

ReferenceSame Category

Risedronic acid

CAS105462-24-6

pharmaceutical raw material

Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Dolutegravir (CAS 1051375-16-6) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide

InChIKey

RHWKPHLQXYSBKR-BMIGLBTASA-N

SMILES

C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O

Synonyms (24)
  • Dolutegravir (USAN)
  • 1051375-16-6 (free)
  • 3s3m
  • 3s3n
  • 3s3o
  • Dolutegravir
  • Dolutegravir (GSK1349572)
  • Dolutegravir (Standard)
  • Dolutegravir DTG
  • GSK 1349572
  • S/GSK1349572
  • S/GSK1349572,GSK1349572
  • Soltegravir
  • Tivicay
  • Tivicay (TN)
  • dolutegravirum

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