C20H18F2N3NaO5
441.4 g/mol
APIWarning
DOLUTEGRAVIR SODIUM
CAS1051375-19-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Dolutegravir sodium is an organic sodium salt and the monosodium salt form of dolutegravir. It is a pharmaceutical raw material used in the manufacturing of HIV-1 integrase inhibitor-based therapies.
Active pharmaceutical ingredient for HIV-1 integrase inhibitor drug productsRaw material for combination antiretroviral therapies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 1051375-19-9
Related Compounds
SimilarStructure SimilarSimilarity 0.80
(4R,12aS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide
CAS1335210-35-9
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.75
Dolutegravir o-benzyl impurity
CAS1206102-11-5
pharmaceutical raw material
ReferenceSame Category
7-methyl-2-(2,2,3,3-tetradeuteriocyclopropyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
CAS1051418-95-1
pharmaceutical raw material
ReferenceSame Category
Tetrabutylammonium acetate
CAS10534-59-5
pharmaceutical raw material
ReferenceSame Category
Ne-58018
CAS105462-23-5
pharmaceutical raw material
ReferenceSame Category
Risedronic acid
CAS105462-24-6
pharmaceutical raw material
Referencestereoisomer of
2H-Pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4S,12aR)-
CAS1309560-49-3
pharmaceutical raw material
Referencestereoisomer of
4-epi-Dolutegravir
CAS1357289-29-2
pharmaceutical raw material
Safety Reference
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H302Harmful if swallowed
Identifiers
IUPAC Name
sodium (3S,7R)-13-[(2,4-difluorophenyl)methylcarbamoyl]-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-olate
InChIKey
UGWJRRXTMKRYNK-VSLILLSYSA-M
SMILES
C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]
Synonyms (13)
- Dolutegravir sodium (JAN/USAN)
- DOLUTEGRAVIR SODIUM
- Dolutegravir sodium salt
- Dovato
- GSK 1349572A
- GSK1349572 sodiuM salt
- GSK1349572 sodium
- TIVICAY PD
- Tivicay
- Tivicay (TN)