C43H69NO12
792 g/mol
APIWarning
Ascomycin
CAS104987-12-4EC435-850-5
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material
Ascomycin, also known as Immunomycin or FR-900520, is an ethyl analog of tacrolimus with strong immunosuppressant properties. It is used as an active pharmaceutical ingredient in research and manufacturing for autoimmune diseases, skin diseases, and organ transplant rejection.
research compound for autoimmune diseasesresearch compound for skin diseasesresearch compound for organ transplant rejection prevention
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 104987-12-4
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StrongStructure SimilarSimilarity 0.90
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Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
InChIKey
ZDQSOHOQTUFQEM-NURRSENYSA-N
SMILES
CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C
Synonyms (28)
- Ascomycin; Tacrolimus EP Impurity A
- Ascomycin (FK520)
- Changchuanmycin
- Immunomycin
- L 683,590
- ascomycin