C21H22N4O3
378.4 g/mol
APIDanger
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
CAS1050477-27-4EC810-201-2
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Finerenone is a non-steroidal mineralocorticoid receptor antagonist used as an active pharmaceutical ingredient. It is supplied as a pharmaceutical raw material for the manufacturing of medications indicated to reduce the risk of kidney function decline, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes, as well as for heart failure with reduced ejection fraction.
Active pharmaceutical ingredient for chronic kidney disease with type 2 diabetesActive pharmaceutical ingredient for heart failure with reduced ejection fraction
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongStructure SimilarSimilarity 0.87
4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid
CAS1050477-45-6
pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.87
(S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic Acid
CAS2640506-74-5
pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.87
(4R)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxylic acid
CAS2883156-66-7
pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.86
5-Desethoxy,-5-Methoxy-Finerenone
CAS2640280-84-6
pharmaceutical raw material
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Safety Reference
Danger
H301Toxic if swallowed
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
InChIKey
BTBHLEZXCOBLCY-UHFFFAOYSA-N
SMILES
CCOC1=NC=C(C2=C1C(C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C
Synonyms (6)
- (Rac)-Finerenone
- Finerenone, (+/-)-
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