Home/Compounds/Pharmaceutical Intermediate/(R)-4-tert-Butoxycarbonyl-1-(benzyloxycarbonyl)piperazine-2-carboxylic acid
C18H24N2O6
364.4 g/mol
Pharmaceutical IntermediateWarning
(R)-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid
CAS954388-33-1
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
This compound is a piperazine derivative functionalized with a tert-butoxycarbonyl (Boc) protecting group and a benzyloxycarbonyl (Cbz) protecting group, bearing a single carboxylic acid group. It is a chiral building block used primarily as an intermediate in the synthesis of active pharmaceutical ingredients.
Pharmaceutical intermediate for API synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 954388-33-1
Related Compounds
StrongStructure SimilarSimilarity 0.91
1-[(Benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylate
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StrongStructure SimilarSimilarity 0.91
4-(Benzyloxycarbonyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
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ReferenceSame Category
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ReferenceSame Category
(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine
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ReferenceSame Category
Rac-tert-butyl (3R,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS955029-44-4
pharmaceutical intermediate
ReferenceSame Category
Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH
CAS955048-92-7
pharmaceutical intermediate
Referencestereoisomer of
N-4-Boc-N-1-Cbz-2-piperazinecarboxylic acid
CAS126937-41-5
pharmaceutical intermediate
Referencestereoisomer of
(S)-N-4-Boc-N-1-Cbz-2-Piperazinecarboxylic acid
CAS150407-69-5
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2R)-4-[(2-methylpropan-2-yl)oxycarbonyl]-1-phenylmethoxycarbonylpiperazine-2-carboxylic acid
InChIKey
MKXMXZZARNRMMQ-CQSZACIVSA-N
SMILES
CC(C)(C)OC(=O)N1CCN([C@H](C1)C(=O)O)C(=O)OCC2=CC=CC=C2
Synonyms (8)
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