C18H24N2O6
364.4 g/mol
Pharmaceutical IntermediateWarning
N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid
CAS126937-41-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a piperazine derivative functionalized with two orthogonal protecting groups: a tert-butoxycarbonyl (Boc) group at the N-4 position and a benzyloxycarbonyl (Cbz) group at the N-1 position, along with a carboxylic acid moiety at the 2-position. It is primarily used as a pharmaceutical intermediate in the synthesis of complex organic molecules, enabling selective deprotection during multi-step manufacturing processes.
Pharmaceutical intermediate for multi-step organic synthesisBuilding block for compounds requiring orthogonal protecting group strategies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 126937-41-5
Related Compounds
StrongStructure SimilarSimilarity 0.91
1-[(Benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylate
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StrongStructure SimilarSimilarity 0.91
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ReferenceSame Category
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ReferenceSame Category
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ReferenceSame Category
1-tert-Butyl 2-methyl piperazine-1,2-dicarboxylate hydrochloride
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ReferenceSame Category
2,5-Dichloro-3-pyridinecarbonitrile
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Referencestereoisomer of
(S)-N-4-Boc-N-1-Cbz-2-Piperazinecarboxylic acid
CAS150407-69-5
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Referencestereoisomer of
(R)-4-tert-Butoxycarbonyl-1-(benzyloxycarbonyl)piperazine-2-carboxylic acid
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pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
4-[(2-methylpropan-2-yl)oxycarbonyl]-1-phenylmethoxycarbonylpiperazine-2-carboxylic acid
InChIKey
MKXMXZZARNRMMQ-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)N1CCN(C(C1)C(=O)O)C(=O)OCC2=CC=CC=C2
Synonyms (15)
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