Home/Compounds/Pharmaceutical Intermediate/(2S,4R)-4-Hydroxypiperidine-1,2-dicarboxylic acid 1-(tert-butyl) ester
C11H19NO5
245.27 g/mol
Pharmaceutical IntermediateWarning
(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid
CAS955016-25-8EC824-270-1
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
This compound is a protected hydroxyproline derivative, specifically a Boc-protected cis-4-hydroxy-D-proline, used as a building block in peptide synthesis. Its stereochemistry is defined, making it valuable for the construction of peptides with precise three-dimensional structure.
Pharmaceutical intermediate for peptide synthesisBuilding block for the preparation of modified peptides
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.74
1-tert-Butyl 2-methyl 4-hydroxypiperidine-1,2-dicarboxylate
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SimilarStructure SimilarSimilarity 0.74
1-Boc-L-azetidine-2-carboxylic acid
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SimilarStructure SimilarSimilarity 0.72
Cis-N-boc-4-hydroxy-D-proline
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ReferenceSame Category
(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine
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ReferenceSame Category
Rac-tert-butyl (3R,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS955029-44-4
pharmaceutical intermediate
ReferenceSame Category
Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH
CAS955048-92-7
pharmaceutical intermediate
ReferenceSame Category
3-Bromo-5-fluoro-4-pyridinecarboxylic acid
CAS955372-86-8
pharmaceutical intermediate
Referencestereoisomer of
(2S,4S)-1-[(tert-Butoxy)carbonyl]-4-hydroxypiperidine-2-carboxylic acid
CAS441044-12-8
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid
InChIKey
GCAZZUFIDGXTDA-SFYZADRCSA-N
SMILES
CC(C)(C)OC(=O)N1CC[C@H](C[C@H]1C(=O)O)O
Synonyms (10)
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