C10H17NO5
231.25 g/mol
Pharmaceutical IntermediateWarning
N-Boc-cis-4-Hydroxy-D-proline
CAS135042-12-5EC621-971-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
N-Boc-cis-4-Hydroxy-D-proline is a protected proline derivative featuring a tert-butoxycarbonyl (Boc) group and a cis-configured hydroxyl group on the pyrrolidine ring. It is primarily used as a building block in peptide synthesis, particularly for introducing stereochemically defined D-proline residues.
Building block in peptide synthesisPharmaceutical intermediate for research and manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 135042-12-5
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Safety Reference
Warning
H319Causes serious eye irritation
Identifiers
IUPAC Name
(2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
InChIKey
BENKAPCDIOILGV-RNFRBKRXSA-N
SMILES
CC(C)(C)OC(=O)N1C[C@@H](C[C@@H]1C(=O)O)O
Synonyms (19)
- Boc-D-cis-Hyp-OH
- Ertapenem Impurity C344
- N-Boc-cis-4-Hydroxy-D-proline