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Home/Compounds/Pharmaceutical Intermediate/Di-tert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
C14H25NO5
287.35 g/mol
Pharmaceutical Intermediate

BOC-HYP-OTBU

CAS170850-75-6
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected derivative of 4-hydroxy-L-proline, featuring both tert-butoxycarbonyl (Boc) and tert-butyl ester protecting groups. It is primarily employed as a building block in solid-phase peptide synthesis, enabling the incorporation of hydroxyproline residues while preventing unwanted side reactions.

Protected amino acid intermediate for peptide synthesisBuilding block for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 170850-75-6

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Identifiers
IUPAC Name

ditert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

InChIKey

OXHIVNUWGSCHBD-ZJUUUORDSA-N

SMILES

CC(C)(C)OC(=O)[C@@H]1C[C@H](CN1C(=O)OC(C)(C)C)O

Synonyms (13)
  • BOC-HYP-OTBU
  • Boc-L-Hyp-OtBu