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Home/Compounds/Pharmaceutical Intermediate/N-Boc-trans-4-Hydroxy-L-proline methyl ester
C11H19NO5
245.27 g/mol
Pharmaceutical Intermediate

(2S,4R)-4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER

CAS74844-91-0
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid derivative used in peptide synthesis. It features a pyrrolidine ring with hydroxyl and ester functional groups, with its stereochemistry defined for specific synthetic applications.

Protected amino acid derivative for peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

Di-tert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

CAS170850-75-6

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.82

1,2-DI-TERT-BUTYL (2S,4S)-4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE

CAS194163-83-2

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

CAS254881-77-1

pharmaceutical intermediate

ReferenceSame Category

1-tert-Butyl 2-methyl (2S)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylate

CAS74844-93-2

pharmaceutical intermediate

ReferenceSame Category

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS74853-08-0

pharmaceutical intermediate

ReferenceSame Category

(2R,4R)-1-[(2S)-5-[[Imino(nitroamino)methyl]amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid ethyl ester

CAS74874-09-2

pharmaceutical intermediate

ReferenceSame Category

(2R,4R)-1-[(2S)-5-[[Imino(nitroamino)methyl]amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid

CAS74874-10-5

pharmaceutical intermediate

Referencestereoisomer of

N-Boc-cis-4-Hydroxy-L-proline methyl ester

CAS102195-79-9

pharmaceutical intermediate

Customs Tariff Classification

The international HS code for (2S,4R)-4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER (CAS 74844-91-0) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

InChIKey

MZMNEDXVUJLQAF-SFYZADRCSA-N

SMILES

CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1C(=O)OC)O

Synonyms (33)
  • BOC-L-HYP-OME
  • Boc-Hyp-OMe
  • rel-Boc-Hyp-OMe

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