Home/Compounds/Pharmaceutical Intermediate/5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
C44H54N7O8P
839.9 g/mol
Pharmaceutical IntermediateWarning
Guanosine, 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-(2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite)
CAS93183-15-4
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate
This compound is a complex organic molecule featuring multiple aromatic rings, ether groups, and a nitrile-containing phosphate ester. It is characterized by high molecular weight and low polarity, and is typically handled as a solid.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 93183-15-4
Related Compounds
SimilarStructure SimilarSimilarity 0.84
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Referencesame scaffold
DMF-dG Phosphoramidite
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Referencesame scaffold
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine
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Safety Reference
Warning
H319Causes serious eye irritation
Identifiers
IUPAC Name
N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChIKey
FDRMKYVTIFSDPR-MMROLVBFSA-N
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
Synonyms (26)
- DMT-dG(iBu)-CE, 0.2% KF
- DMT-dG(ib) Pharmadite(R)
- DMT-dG(ib) Phosphoramidite
- Guanosine Impurity 4
- dG(N-ibu)Phosphoramidite
- ibu-dG Phosphoramidite