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Home/Compounds/API/3-[[4-[methyl-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylic acid methyl ester
C31H33N5O4
539.6 g/mol
API

Nintedanib

CAS928326-83-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Nintedanib is a kinase inhibitor active pharmaceutical ingredient used in the manufacturing of medications for idiopathic pulmonary fibrosis and certain types of non-small-cell lung cancer.

pharmaceutical raw material for idiopathic pulmonary fibrosis therapiespharmaceutical intermediate for non-small-cell lung cancer treatments

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Nintedanib

CAS656247-17-5

pharmaceutical raw material

StrongSame Parent

Nintedanib esylate

CAS656247-18-6

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.82

Intedanib Piperazinyl-N4-oxide

CAS2734666-06-7

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.82

Intedanib Piperazinyl-N4-oxide

CAS3029792-02-4

research compound

SimilarStructure SimilarSimilarity 0.77

(Z)-1-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1-oxide

CAS3029792-00-2

research compound

ApplicationSame Use

Ripretinib

CAS1442472-39-0

pharmaceutical raw material

ReferenceSame Category

Canagliflozin hemihydrate

CAS928672-86-0

pharmaceutical raw material

ReferenceSame Category

Seladelpar lysine dihydrate

CAS928821-40-3

pharmaceutical raw material

Identifiers
IUPAC Name

methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate

InChIKey

CPMDPSXJELVGJG-UHFFFAOYSA-N

SMILES

CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O

Synonyms (38)
  • OFEV
  • Nintedanib (USAN/INN)
  • (E)-Nintedanib
  • BIBF 1120
  • BIBF1120,Vargatef
  • Intedanib
  • Nintedanib
  • Nintedanib (BIBF 1120)
  • Nintedanib (Standard)
  • Nintedanib - Bio-X trade mark
  • Nintedanib D3
  • Nintedanib E-isomer
  • Nintedanib, Free Base
  • OFEV COMPONENT NINTEDANIB
  • Ofev (TN)
  • US10669235, Nintedanib
  • Vargatef