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Home/Compounds/API/Nintedanib
C31H33N5O4
539.6 g/mol
API

Nintedanib

CAS656247-17-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Nintedanib is an active pharmaceutical ingredient used in the manufacturing of oral medications for certain fibrotic and oncologic conditions. It is a small-molecule compound supplied as a raw material for pharmaceutical formulation and research.

Idiopathic pulmonary fibrosis medicationNon-small-cell lung cancer medication

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 656247-17-5

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Related Compounds

StrongSame Parent

Nintedanib esylate

CAS656247-18-6

pharmaceutical raw material

StrongSame Parent

3-[[4-[methyl-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylic acid methyl ester

CAS928326-83-4

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.82

Intedanib Piperazinyl-N4-oxide

CAS2734666-06-7

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.82

Intedanib Piperazinyl-N4-oxide

CAS3029792-02-4

research compound

SimilarStructure SimilarSimilarity 0.77

(Z)-1-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1-oxide

CAS3029792-00-2

research compound

ReferenceSame Category

Silymarin

CAS65666-07-1

pharmaceutical raw material

ReferenceSame Category

Metformin

CAS657-24-9

pharmaceutical raw material

ReferenceSame Category

Apramycin sulfate

CAS65710-07-8

pharmaceutical raw material

Identifiers
IUPAC Name

methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate

InChIKey

CPMDPSXJELVGJG-UHFFFAOYSA-N

SMILES

CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O

Synonyms (38)
  • OFEV
  • Nintedanib (USAN/INN)
  • (E)-Nintedanib
  • BIBF 1120
  • BIBF1120,Vargatef
  • Intedanib
  • Nintedanib
  • Nintedanib (BIBF 1120)
  • Nintedanib (Standard)
  • Nintedanib - Bio-X trade mark
  • Nintedanib D3
  • Nintedanib E-isomer
  • Nintedanib, Free Base
  • OFEV COMPONENT NINTEDANIB
  • Ofev (TN)
  • US10669235, Nintedanib
  • Vargatef