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Home/Compounds/API/Ripretinib
C24H21BrFN5O2
510.4 g/mol
API

Ripretinib

CAS1442472-39-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Ripretinib is a kinase inhibitor used as a pharmaceutical raw material for the manufacturing of advanced gastrointestinal stromal tumor (GIST) therapy. It is indicated for cases that have not adequately responded to other kinase inhibitors such as sunitinib and imatinib.

pharmaceutical raw material for GIST therapyresearch compound for kinase inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 1442472-39-0

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Identifiers
IUPAC Name

1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea

InChIKey

CEFJVGZHQAGLHS-UHFFFAOYSA-N

SMILES

CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC

Synonyms (19)
  • Ripretinib (USAN)
  • 1442472-39-0 (free base)
  • KIT/PDGFR Inhibitor DCC-2618
  • Qinlock (TN)
  • Quinlock
  • Ripretinib
  • Ripretinib (DCC-2618)
  • Ripretinib free base
  • qinlock
  • ripretinibum