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Home/Compounds/API/Paroxetine hydrochloride
C19H21ClFNO3
365.8 g/mol
APIDanger

Paroxetine hydrochloride

CAS78246-49-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Paroxetine hydrochloride is an active pharmaceutical ingredient in the selective serotonin reuptake inhibitor (SSRI) class, primarily used in the manufacturing of antidepressant medications. It is a salt-form compound with moderate lipophilicity and contains amine, ether, and halogen functional groups.

Pharmaceutical raw material for antidepressant formulationsCompound used in manufacturing of SSRIsAPI for research and development in psychiatry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Paroxetine hydrochloride hemihydrate

CAS110429-35-1

pharmaceutical raw material

StrongStructure SimilarSimilarity 0.94

Rac-trans-4-Defluoro-4-(4-fluorophenyl) Paroxetine Hydrochloride

CAS1217655-87-2

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

Paroxetine EP Impurity A HCl

CAS324024-00-2

pharmaceutical raw material

ReferenceSame Category

Rosiptor

CAS782487-28-9

pharmaceutical raw material

ReferenceSame Category

Nepafenac

CAS78281-72-8

pharmaceutical raw material

ReferenceSame Category

Milrinone

CAS78415-72-2

pharmaceutical raw material

ReferenceSame Category

10-deacetylpaclitaxel

CAS78432-77-6

pharmaceutical raw material

Referencesame scaffold

N-methylparoxetine

CAS110429-36-2

pharmaceutical intermediate

Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Environmental Hazard
Environmental Hazard
Danger
H302Harmful if swallowed
H318Causes serious eye damage
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name

(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrochloride

InChIKey

GELRVIPPMNMYGS-RVXRQPKJSA-N

SMILES

C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl

Synonyms (37)
  • Paroxetine hydrochloride (USP)
  • Paroxetine hydrochloride [EP monograph]
  • Aropax 20
  • BRL 29060 hydrochloride
  • BRL 29060A
  • Deroxat
  • Paroxat
  • Paroxetine HCl (hemihydrate)
  • Paroxetine Hcl
  • Paroxetine Impurity Standard
  • Paroxetine hydrochloride
  • Paxil
  • Paxil (TN)
  • Paxil CR
  • Paxilcr CR
  • Seroxat