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Home/Compounds/API/Nepafenac
C15H14N2O2
254.28 g/mol
APIWarning

Nepafenac

CAS78281-72-8EC682-241-7
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Nepafenac is a monocarboxylic acid amide and a prodrug of amfenac, functioning as a non-steroidal anti-inflammatory agent that inhibits cyclooxygenase enzymes. It is used as a pharmaceutical raw material in eye drops for the management of pain and inflammation following cataract surgery.

pharmaceutical raw material for anti-inflammatory eye dropsprodrug for postoperative ocular pain and inflammation management

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.75

Amfenac sodium hydrate

CAS61618-27-7

pharmaceutical raw material

ReferenceSame Category

Milrinone

CAS78415-72-2

pharmaceutical raw material

ReferenceSame Category

10-deacetylpaclitaxel

CAS78432-77-6

pharmaceutical raw material

ReferenceSame Category

Ceftazidime pentahydrate

CAS78439-06-2

pharmaceutical raw material

ReferenceSame Category

Amorolfine

CAS78613-35-1

pharmaceutical raw material

Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H400Very toxic to aquatic life

Customs Tariff Classification

The international HS code for Nepafenac (CAS 78281-72-8) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-(2-amino-3-benzoylphenyl)acetamide

InChIKey

QEFAQIPZVLVERP-UHFFFAOYSA-N

SMILES

C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N

Synonyms (17)
  • Nepafenac (JAN/USAN/INN)
  • AHR 9434;AL 6515
  • Amfenac amide
  • Ilevro
  • NEPAFENAC [MART.]
  • Nepafenac
  • Nepafenac (Standard)
  • Nepafenac, >=98% (HPLC)
  • Nevanac
  • Nevanac (TN)
  • nepafenaco
  • nepafenacum

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