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Home/Compounds/API/Paroxetine hydrochloride hemihydrate
C38H44Cl2F2N2O7
749.7 g/mol
APIWarning

Paroxetine hydrochloride hemihydrate

CAS110429-35-1
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Paroxetine hydrochloride hemihydrate is a salt and hydrate form of paroxetine, a selective serotonin reuptake inhibitor (SSRI) used as an active pharmaceutical ingredient. It is primarily employed in the manufacturing of medications for psychiatric and neurological conditions.

Pharmaceutical raw material for antidepressant formulationsCompound used in manufacturing of SSRIs

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Paroxetine hydrochloride

CAS78246-49-8

pharmaceutical raw material

StrongStructure SimilarSimilarity 0.94

Rac-trans-4-Defluoro-4-(4-fluorophenyl) Paroxetine Hydrochloride

CAS1217655-87-2

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

Paroxetine EP Impurity A HCl

CAS324024-00-2

pharmaceutical raw material

ReferenceSame Category

Calcium bis[(3R,5R)-7-({(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl}amino)-3,5-dihydroxyheptanoate]

CAS1105067-87-5

pharmaceutical raw material

ReferenceSame Category

Exubera

CAS11061-68-0

pharmaceutical raw material

ReferenceSame Category

Ambrisentan acyl β-D-glucuronide

CAS1106685-58-8

pharmaceutical raw material

ReferenceSame Category

4-hydroxymethyl ambrisentan

CAS1106685-66-8

pharmaceutical raw material

Referencesame scaffold

N-methylparoxetine

CAS110429-36-2

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Paroxetine hydrochloride hemihydrate (CAS 110429-35-1) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

bis((3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine);hydrate;dihydrochloride

InChIKey

MQZOATSIFWSKKT-OASXIEIISA-N

SMILES

C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.O.Cl.Cl

Synonyms (23)
  • Paroxetine hydrochloride hemihydrate (USP)
  • Aeopax
  • PAROXETINE HCL HEMIHYDRATE
  • PAROXETINE HYDROCHLORIDE
  • Paroxetine HCl hydrate
  • Paxil
  • Paxil (TN)
  • Seroxat

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