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Home/Compounds/API/Tesevatinib
C24H25Cl2FN4O2
491.4 g/mol
API

N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,6aS)-2-methyloctahydrocyclopenta(c)pyrrol-5-yl)methoxy)-4-quinazolinamine

CAS781613-23-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Tesevatinib is a quinazoline-based compound that functions as a multi-target tyrosine kinase inhibitor, targeting receptors such as EGFR, ErbB2, KDR, Flt4, and EphB4. It is investigated for its anticancer properties and is used as a pharmaceutical raw material or research compound.

Pharmaceutical raw material for kinase inhibitor researchLaboratory reagent for cancer research studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 781613-23-8

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Identifiers
IUPAC Name

7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine

InChIKey

HVXKQKFEHMGHSL-GOOCMWNKSA-N

SMILES

CN1C[C@H]2CC(C[C@H]2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC

Synonyms (19)
  • EX-A172
  • KD-019
  • KD-020
  • XL-647
  • Tesevatinib (USAN/INN)
  • EXEL 7647
  • Tesevatinib
  • US9796704, Entry 9
  • XL-647;EXEL-7647;KD-019
  • tesevatinibum