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Home/Compounds/API/2-[[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
C13H17N5O8S2
435.4 g/mol
APIDanger

Aztreonam

CAS78110-38-0EC278-839-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used as an active pharmaceutical ingredient for infections involving gram-negative bacteria, particularly of the meninges, bladder, and kidneys.

Pharmaceutical raw material for gram-negative infection therapyAntibiotic manufacturing intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 78110-38-0

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H315Causes skin irritation
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
Identifiers
IUPAC Name

2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid

InChIKey

WZPBZJONDBGPKJ-VEHQQRBSSA-N

SMILES

C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)NC(=O)/C(=N\OC(C)(C)C(=O)O)/C2=CSC(=N2)N

Synonyms (41)
  • A-9950
  • Aztreonam, United States Pharmacopeia (USP)
  • AZACTAM IN PLASTIC CONTAINER
  • AZTREONAM [MART.]
  • Azactam
  • Azetreonam
  • Azonam
  • Azthreonam
  • Aztreon
  • Aztreonam (Anhydrous)
  • Aztreonam (Standard)
  • Aztreonamum
  • Cayston
  • Dynabiotic;
  • EMBLAVEO COMPONENT AZTREONAM
  • Monobactam;
  • Nebactam
  • Primbactam
  • Probactam
  • SQ 26,776
  • Squibb 26776
  • aztreonam
  • rel-Aztreonam