C24H23FN4O3
434.5 g/mol
APIDanger
Olaparib
CAS763113-22-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Olaparib is a compound that functions as a poly(ADP-ribose) polymerase (PARP) inhibitor, used in pharmaceutical manufacturing. It is a member of the N-acylpiperazine class and is employed as an antineoplastic agent, specifically as an apoptosis inducer via inhibition of NAD(+) ADP-ribosyltransferase.
Pharmaceutical raw material for antineoplastic therapyPoly(ADP-ribose) polymerase inhibitor in drug manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 763113-22-0
Related Compounds
SimilarStructure SimilarSimilarity 0.78
4-{[3-(4-acetylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one
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SimilarStructure SimilarSimilarity 0.76
4-{[4-fluoro-3-(piperazine-1-carbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one
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SimilarStructure SimilarSimilarity 0.75
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Safety Reference
Danger
H301Toxic if swallowed
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
InChIKey
FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES
C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Synonyms (33)
- Olaparib (JAN/USAN/INN)
- AZD2281(olaparib)
- AZD2281,Olaparib, KU-0059436
- Lynparza
- Lynparza (TN)
- OLAPARIB [MART.]
- OLAPARIB cpd
- Olaparib
- Olaparib (AZD-2281)
- Olaparib (DISCONTINUED)
- Olaparib (Standard)
- Olaparib - Bio-X trade mark
- Olaparib, KU-0059436
- Olaparibum
- PARP inhibitor AZD2281