C18H24N2O5
348.4 g/mol
APIWarning
Enalaprilat
CAS76420-72-9EC278-459-3
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material
Enalaprilat is the active metabolite of the drug enalapril and the first dicarboxylate-containing angiotensin-converting enzyme (ACE) inhibitor. It was developed to improve upon the limitations of earlier ACE inhibitors by replacing a thiol group with a carboxylic acid group while maintaining comparable potency.
active pharmaceutical ingredientcompound used in pharmaceutical manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 76420-72-9
Related Compounds
SimilarStructure SimilarSimilarity 0.81
(2S)-1-((2S)-2-(((1R)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid
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pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.81
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Referencestereoisomer of
Enalaprilat D5
CAS349554-00-3
pharmaceutical raw material
Referencesame scaffold
Lisinopril
CAS76547-98-3
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name
(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
InChIKey
LZFZMUMEGBBDTC-QEJZJMRPSA-N
SMILES
C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O
Synonyms (32)
- EAL
- Enalapril Maleate EP Impurity C
- ENALAPRIL MALEATE IMPURITY C
- ENALAPRILAT INHIBITOR
- Enalapril acid
- Enalapril diacid
- Enalapril diacid dihydrate
- Enalaprilat
- Enalaprilat anhydrous
- Enalaprilate
- Enalaprilate [French]
- Enalaprilatum
- Enalaprilatum [Latin]
- Enalaprilic acid
- MK 421 diacid
- Vasotec i.v.
- enalaprilat [Spanish]