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Home/Compounds/API/Enalaprilat
C18H24N2O5
348.4 g/mol
APIWarning

Enalaprilat

CAS76420-72-9EC278-459-3
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Enalaprilat is the active metabolite of the drug enalapril and the first dicarboxylate-containing angiotensin-converting enzyme (ACE) inhibitor. It was developed to improve upon the limitations of earlier ACE inhibitors by replacing a thiol group with a carboxylic acid group while maintaining comparable potency.

active pharmaceutical ingredientcompound used in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.81

(2S)-1-((2S)-2-(((1R)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid

CAS76420-74-1

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

Enalapril maleate

CAS76095-16-4

pharmaceutical raw material

ReferenceSame Category

Sultamicillin

CAS76497-13-7

pharmaceutical raw material

ReferenceSame Category

Lexidronam pentasodium

CAS7651-99-2

pharmaceutical raw material

ReferenceSame Category

Alclometasone 17-propionate

CAS76576-24-4

pharmaceutical raw material

ReferenceSame Category

Valproate semisodium

CAS76584-70-8

pharmaceutical raw material

Referencestereoisomer of

Enalaprilat D5

CAS349554-00-3

pharmaceutical raw material

Referencesame scaffold

Lisinopril

CAS76547-98-3

pharmaceutical raw material

Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed

Customs Tariff Classification

The international HS code for Enalaprilat (CAS 76420-72-9) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid

InChIKey

LZFZMUMEGBBDTC-QEJZJMRPSA-N

SMILES

C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O

Synonyms (32)
  • EAL
  • Enalapril Maleate EP Impurity C
  • ENALAPRIL MALEATE IMPURITY C
  • ENALAPRILAT INHIBITOR
  • Enalapril acid
  • Enalapril diacid
  • Enalapril diacid dihydrate
  • Enalaprilat
  • Enalaprilat anhydrous
  • Enalaprilate
  • Enalaprilate [French]
  • Enalaprilatum
  • Enalaprilatum [Latin]
  • Enalaprilic acid
  • MK 421 diacid
  • Vasotec i.v.
  • enalaprilat [Spanish]

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