Home/Compounds/Pharmaceutical Intermediate/4-{[4-fluoro-3-(piperazine-1-carbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one
C20H19FN4O2
366.4 g/mol
Pharmaceutical IntermediateWarning
4-{[4-fluoro-3-(piperazine-1-carbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one
CAS763111-47-3EC881-419-3
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a pharmaceutical intermediate specifically used in the manufacture of olaparib. It features a fluorinated aromatic ring and a piperazine carboxamide moiety, contributing to its role as a key building block in drug synthesis.
Intermediate for olaparib synthesisBuilding block in pharmaceutical manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.80
4-{[3-(4-acetylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one
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SimilarStructure SimilarSimilarity 0.76
Olaparib
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SimilarStructure SimilarSimilarity 0.73
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ReferenceSame Category
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ReferenceSame Category
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Safety Reference
Warning
H317May cause an allergic skin reaction
H371May cause damage to organs
Identifiers
IUPAC Name
4-[[4-fluoro-3-(piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
InChIKey
MFFUYEOGICAKCK-UHFFFAOYSA-N
SMILES
C1CN(CCN1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F
Synonyms (13)
- Olaparib Impurity E
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