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Home/Compounds/Pharmaceutical Intermediate/N-Cbz-Piperidine-2-carboxylic acid
C14H17NO4
263.29 g/mol
Pharmaceutical IntermediateWarning

1-Carbobenzoxy-2-piperidinecarboxylic Acid

CAS71170-88-2EC818-916-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

1-Carbobenzoxy-2-piperidinecarboxylic acid is a protected piperidine derivative used primarily as a building block in peptide synthesis. Its structure features a carbobenzoxy (Cbz) protecting group attached to the nitrogen atom of the piperidine ring, with a carboxylic acid functional group available for further coupling reactions.

pharmaceutical intermediate for peptide synthesisbuilding block in the production of peptide-based compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.92

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SimilarStructure SimilarSimilarity 0.83

1-(1-phenylmethoxycarbonylpyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid

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Benzyl L-leucinate--hydrogen chloride (1/1)

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ReferenceSame Category

Ethyl 1-N-Boc-3-oxopiperidine-4-carboxylate

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

1-phenylmethoxycarbonylpiperidine-2-carboxylic acid

InChIKey

ZSAIHAKADPJIGN-UHFFFAOYSA-N

SMILES

C1CCN(C(C1)C(=O)O)C(=O)OCC2=CC=CC=C2

Synonyms (21)
  • (l)-n-cbz-pipecolic acid
  • Cbz-DL-Pip-OH
  • N-cbz-pipecolic acid
  • Z-D-homoproline
  • Z-L-homoproline
  • Z-pipecolic acid

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