C13H15NO4
249.26 g/mol
Pharmaceutical IntermediateWarning
N-(Benzyloxycarbonyl)-D-proline
CAS6404-31-5EC229-021-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
N-(Benzyloxycarbonyl)-D-proline, commonly referred to as Cbz-D-Pro-OH, is a protected amino acid derivative used as a reagent in peptide synthesis. Its significance lies in its role as a protecting group reagent, where the benzyloxycarbonyl (Cbz) group temporarily shields the amino function during peptide chain assembly.
Peptide synthesis protecting group reagentLaboratory research intermediate for peptide manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongStructure SimilarSimilarity 0.92
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StrongStructure SimilarSimilarity 0.90
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SimilarStructure SimilarSimilarity 0.80
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ReferenceSame Category
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Related Reading
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for N-(Benzyloxycarbonyl)-D-proline (CAS 6404-31-5) is 2933.99.
HS code (international, 6-digit)
2933.99
EU CN code (8-digit)
2933 99 80
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(2R)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
InChIKey
JXGVXCZADZNAMJ-LLVKDONJSA-N
SMILES
C1C[C@@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O
Synonyms (26)
- (+)-CARBOBENZYLOXY-D-PROLINE
- CBZ-D-PROLINE
- CBZ-PRO-OH
- Cbz-D-Pro-OH
- D-Cbz-Proline
- N-(Carbobenzyloxy)-D-proline
- N-Carbobenzoxy-D-proline
- N-Cbz-D-proline
- N-benzyloxycarbonyI-D-proline
- Z-D-PROLINE
- Z-D-Pro-OH
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