C14H19NO4
265.3 g/mol
Pharmaceutical IntermediateWarning
N-Benzyloxycarbonyl-L-leucine
CAS2018-66-8EC217-960-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
N-Benzyloxycarbonyl-L-leucine is a chemical compound used as a protecting group reagent in peptide synthesis. It is also the substrate for the enzyme Nα-benzyloxycarbonylleucine hydrolase, which catalyzes its hydrolysis to benzyl alcohol, carbon dioxide, and L-leucine.
Peptide synthesis protecting group reagentEnzyme substrate for Nα-benzyloxycarbonylleucine hydrolase studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 2018-66-8
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Safety Reference
Warning
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name
(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid
InChIKey
USPFMEKVPDBMCG-LBPRGKRZSA-N
SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1
Synonyms (45)
- Benzyloxycarbonyl-L-leucine
- Benzyloxycarbonylleucine
- CBZ-L-Leu
- Carbobenzoxy-L-leucine
- Carbobenzoxyleucine
- Carbobenzyloxy-L-leucine
- Cbz-L-LeuOH
- Cbz-Leu
- Cbz-Leucine
- L-(Carbobenzyloxy)leucine
- N-(Carbobenzoxy)leucine
- N-ALPHA-CBZ-L-LEUCINE
- N-Benzyloxycarbonyl-L-leucine
- N-Benzyloxycarbonylleucine
- N-Carbobenzoxy-L-leucine
- N-Carbobenzyloxy-L-leucine
- N-Cbz-L-leucine
- N-Cbz-leucine
- N-Z-Leu-OH
- N-benzoxycarbonyl-L-leucine
- N-benzyloxycarbonyl-leucin
- Z-L-Leucine
- Z-Leu
- Z-Leu-OH
- Z-Leu-OH, purum, >=96.0% (T)
- cbz-l-leucine
- cbz-leu-oh
- n-carbobenzyloxyleucine