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Home/Compounds/Pharmaceutical Intermediate/N-(carbobenzyloxy)-L-proline
C13H15NO4
249.26 g/mol
Pharmaceutical IntermediateDanger

Carbobenzoxyproline

CAS1148-11-4EC214-557-4
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Carbobenzoxyproline is a protected amino acid derivative commonly used in peptide synthesis. It features a carbobenzoxy (Cbz) protecting group attached to the nitrogen of proline, making it a valuable intermediate in pharmaceutical manufacturing.

Peptide synthesis intermediatePharmaceutical intermediate for research and manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Danger
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Carbobenzoxyproline (CAS 1148-11-4) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid

InChIKey

JXGVXCZADZNAMJ-NSHDSACASA-N

SMILES

C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O

Synonyms (48)
  • 1-(Benzyloxycarbonyl)proline
  • 1-Carbobenzoxy-L-proline
  • Benzyloxycarbonyl-L-proline
  • Benzyloxycarbonylproline
  • CBZ-L-PRO-OH
  • CBZ-L-PROLINE
  • CBZ-PRO-OH
  • Carbobenzoxy-L-proline
  • Carbobenzoxy-S-proline
  • Carbobenzoxyproline
  • Carbobenzyloxy-L-proline
  • Cbz-Pro
  • L-CBZ-PROLINE
  • N-(Carbobenzyloxy)-L-proline
  • N-Benzyloxycarbonyl-L-proline
  • N-Benzyloxycarbonylproline
  • N-CBZ-L-PROLINE
  • N-Carbobenzoxy-L-proline
  • N-benzoxycarbonyl-L-Proline
  • N-carbobenzoxy-l-pro
  • N-carbobenzoxyproline
  • Z-L-PRO-OH
  • Z-L-Proline
  • Z-Pro
  • Z-Pro-OH
  • carbobenzyloxyproline
  • cbz-proline
  • n-cbz-proline

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