C12H12N2O4S2
312.4 g/mol
Research ReagentWarning
SPDP
CAS68181-17-9EC269-034-3
Category
Research Reagent
Compound Class
Ester
Primary Use
Research Compound
SPDP is a heterobifunctional crosslinking reagent used in biochemical research. It contains an amine-reactive N-hydroxysuccinimide ester and a pyridyldithiol group that reacts with thiols, enabling the conjugation of proteins and other molecules.
conjugation of antibodies to enzymes or toxinscrosslinking peptides or proteins for structural studieslaboratory reagent for bioconjugation reactions
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 68181-17-9
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-(pyridin-2-yldisulfanyl)propanoate
InChIKey
JWDFQMWEFLOOED-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)CCSSC2=CC=CC=N2
Synonyms (26)
- SIPDTP
- SPDP
- SPDP-OSU
- SPDP (2mg*5)
- SPDP (SPDP Crosslinker)
- SPDP Crosslinker
- SPDP NHS ester
- SPDP acid NHS ester