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Home/Compounds/Pharmaceutical Intermediate/Hoxd13
C15H18N2O4S2
354.4 g/mol
Pharmaceutical Intermediate

SPDH

CAS1824718-79-7
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

SPDH is a heterobifunctional crosslinking reagent featuring an N-hydroxysuccinimide (NHS) ester and a pyridyldisulfide group, connected by a hexanoate spacer. It is primarily used as a pharmaceutical intermediate for bioconjugation, enabling the formation of cleavable disulfide bonds between biomolecules.

Pharmaceutical intermediate for bioconjugationCrosslinking reagent for antibody-drug conjugate synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 6-(pyridin-2-yldisulfanyl)hexanoate

InChIKey

GUNOUNRTBRPXOQ-UHFFFAOYSA-N

SMILES

C1CC(=O)N(C1=O)OC(=O)CCCCCSSC2=CC=CC=N2

Synonyms (4)
  • SPDH