C21H24N8O5
468.5 g/mol
Pharmaceutical IntermediateDanger
Methotrexate 5-methyl ester
CAS67022-39-3
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
Methotrexate 5-methyl ester is a chemical compound that serves as a pharmaceutical intermediate for the production of methotrexate derivatives. It is characterized by its complex aromatic and heterocyclic structure.
pharmaceutical intermediate for methotrexate derivatives
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 67022-39-3
Related Compounds
StrongStructure SimilarSimilarity 0.87
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Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
Identifiers
IUPAC Name
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
InChIKey
RYGFOBBTCUXHBB-AWEZNQCLSA-N
SMILES
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)OC)C(=O)O
Synonyms (14)
- L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 5-methyl ester; Methotrexate 5-Methyl Ester; Methotrexate Imp. H (EP); Methotrexate Related Compound H; Methotrexate Impurity H
- METHOTREXATE IMPURITY H (EP IMPURITY)
- Methotrexate EP Impurity H
- METHOTREXATE IMPURITY H
- Methotrexate 5-methyl ester
- Methotrexate ?-Methyl Ester
- Methotrexate |A-Methyl Ester