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Home/Compounds/API/Folinic acid
C20H23N7O7
473.4 g/mol
API

Folinic acid

CAS58-05-9EC200-361-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Folinic acid, also known as leucovorin, is a pharmaceutical active ingredient used to reduce the toxic effects of certain drugs and as a component in chemotherapy regimens for specific cancers.

pharmaceutical raw material for reducing methotrexate toxicitypharmaceutical raw material for reducing pyrimethamine toxicitypharmaceutical raw material for combination therapy with 5-fluorouracil

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.81

5-methyltetrahydrofolic acid

CAS134-35-0

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

Levomefolic acid

CAS31690-09-2

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.72

4-[[[(6S)-2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoic acid

CAS944737-05-7

research compound

SimilarStructure SimilarSimilarity 0.72

5-Formyltetrahydropteroic acid

CAS4349-43-3

pharmaceutical intermediate

ApplicationSame Use

L-(+)-methylenetetrahydrofolic acid

CAS31690-11-6

pharmaceutical raw material

ApplicationSame Use

(-)-homoharringtonine

CAS26833-87-4

pharmaceutical raw material

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Mebeverine hydrochloride

CAS2753-45-9

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Sn-glycero-3-phosphocholine

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pharmaceutical raw material

Customs Tariff Classification

The international HS code for Folinic acid (CAS 58-05-9) is 2936.29.

HS code (international, 6-digit)

2936.29

EU CN code (8-digit)

2936 29 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

InChIKey

VVIAGPKUTFNRDU-ABLWVSNPSA-N

SMILES

C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

Synonyms (50)
  • 5-Formyltetrahydrofolic acid
  • 5-formyl-THF
  • 5-formyltetrahydrofolate
  • Acid, Folinic
  • Acide folinique
  • Citrovoeum factor
  • FOLINIC ACID [MART.]
  • Folinate, Calcium
  • Folinic acid (Standard)
  • Folinic acid-SF
  • L-(+)-Folinic acid
  • Leucal
  • Leucoverin
  • Leucovorin, Calcium
  • Leucovorinum
  • Leucovorinum (acid)
  • Leukovorin
  • Leukovorum
  • Monosodium Salt Leucovorin
  • N5-Formyltetrahydrofolic acid
  • Welcovorin
  • Wellcovorin
  • [3H]folinic acid
  • folinate
  • folinic acid
  • l-Leucovorin
  • leucovorin

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