C20H25N7O6
459.5 g/mol
APIWarning
5-METHYLTETRAHYDROFOLIC ACID
CAS134-35-0EC603-809-2
Category
API
Compound Class
Organic Acid
Primary Use
Pharmaceutical Raw Material
5-Methyltetrahydrofolic acid, also known as levomefolic acid or L-5-MTHF, is the primary biologically active form of folate used at the cellular level. It plays a key role in DNA reproduction, the cysteine cycle, and the regulation of homocysteine, and is the form found in circulation and transported across membranes into tissues and the blood-brain barrier.
Active pharmaceutical ingredient in pharmaceutical manufacturingCompound used in research for homocysteine regulation studiesLaboratory reagent for methylation pathway investigations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.81
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Referencestereoisomer of
Levomefolate calcium
CAS151533-22-1
pharmaceutical raw material
Referencestereoisomer of
Calcium mefolinate
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pharmaceutical raw material
Safety Reference
Warning
H317May cause an allergic skin reaction
Identifiers
IUPAC Name
(2S)-2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
InChIKey
ZNOVTXRBGFNYRX-ABLWVSNPSA-N
SMILES
CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Synonyms (26)
- 5-METHYLTETRAHYDROFOLIC ACID
- 5-Methyl terahydrofolic acid
- 5-Methyltetrahydrofolate
- 5-methyl-THF
- MEFOLIC ACID
- Methyl folate
- N-Methyltetrahydrofolic acid
- Prefolic A
- n-methyltetrahydrofolate
- n5-methyltetrahydrofolate
- n5-methyltetrahydrofolic acid
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