ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/API/5-methyltetrahydrofolic acid
C20H25N7O6
459.5 g/mol
APIWarning

5-METHYLTETRAHYDROFOLIC ACID

CAS134-35-0EC603-809-2
Category
API
Compound Class
Organic Acid
Primary Use
Pharmaceutical Raw Material

5-Methyltetrahydrofolic acid, also known as levomefolic acid or L-5-MTHF, is the primary biologically active form of folate used at the cellular level. It plays a key role in DNA reproduction, the cysteine cycle, and the regulation of homocysteine, and is the form found in circulation and transported across membranes into tissues and the blood-brain barrier.

Active pharmaceutical ingredient in pharmaceutical manufacturingCompound used in research for homocysteine regulation studiesLaboratory reagent for methylation pathway investigations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 134-35-0

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

SimilarStructure SimilarSimilarity 0.81

Folinic acid

CAS58-05-9

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

Levoleucovorin

CAS68538-85-2

pharmaceutical intermediate

ReferenceSame Category

Erythromycin propionate

CAS134-36-1

pharmaceutical raw material

ReferenceSame Category

Aminacrine hydrochloride

CAS134-50-9

pharmaceutical raw material

ReferenceSame Category

8-azaguanine

CAS134-58-7

pharmaceutical raw material

ReferenceSame Category

Lobeline hydrochloride

CAS134-63-4

pharmaceutical raw material

Referencestereoisomer of

Levomefolate calcium

CAS151533-22-1

pharmaceutical raw material

Referencestereoisomer of

Calcium mefolinate

CAS26560-38-3

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Warning
H317May cause an allergic skin reaction
Identifiers
IUPAC Name

(2S)-2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

InChIKey

ZNOVTXRBGFNYRX-ABLWVSNPSA-N

SMILES

CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

Synonyms (26)
  • 5-METHYLTETRAHYDROFOLIC ACID
  • 5-Methyl terahydrofolic acid
  • 5-Methyltetrahydrofolate
  • 5-methyl-THF
  • MEFOLIC ACID
  • Methyl folate
  • N-Methyltetrahydrofolic acid
  • Prefolic A
  • n-methyltetrahydrofolate
  • n5-methyltetrahydrofolate
  • n5-methyltetrahydrofolic acid