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Home/Compounds/API/L-(+)-methylenetetrahydrofolic acid
C20H23N7O6
457.4 g/mol
API

Arfolitixorin

CAS31690-11-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Arfolitixorin is the (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid, a reduced folate derivative that acts as a cofactor in one-carbon metabolism. It is also a metabolite found in Escherichia coli and has been investigated for use in pharmaceutical research.

research compound for osteosarcoma studiesbiochemical reagent in one-carbon metabolism research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(2S)-2-[[4-[(6aR)-3-amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl]benzoyl]amino]pentanedioic acid

InChIKey

QYNUQALWYRSVHF-OLZOCXBDSA-N

SMILES

C1[C@@H]2CN(CN2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)N[C@@H](CCC(=O)O)C(=O)O

Synonyms (35)
  • 6R-MTHF
  • Arfolitixorin (USAN/INN)
  • Calcium Levofolinate EP Impurity I
  • (6R)-5,10-MTHF
  • 5,10-methylene-THF
  • 6R-5,10-methyleneTHF
  • 6R-methylene THF
  • Arfolitixorin
  • Arfolitixorina
  • Arfolitixorine
  • Modufolin
  • arfolitixorin sulfate
  • arfolitixorinum