C19H26ClNO6
399.9 g/mol
APIWarning
Naloxone hydrochloride dihydrate
CAS51481-60-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Naloxone hydrochloride dihydrate is a salt and hydrate form of the opioid antagonist naloxone. It is used as an active pharmaceutical ingredient (API) in drug products for reversing or reducing the effects of opioid overdoses.
pharmaceutical raw material for opioid overdose reversal productsAPI in injectable and nasal spray formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 51481-60-8
Related Compounds
StrongSame Parent
Naloxone hydrochloride
CAS357-08-4
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.79
Naloxone 3-Methyl Ether
CAS70866-64-7
research compound
SimilarStructure SimilarSimilarity 0.75
Naltrexone
CAS16590-41-3
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.75
Naltrexone hydrochloride
CAS16676-29-2
pharmaceutical raw material
ReferenceSame Category
Cimetidine
CAS51481-61-9
pharmaceutical raw material
ReferenceSame Category
Sulfisomidine
CAS515-64-0
pharmaceutical raw material
ReferenceSame Category
(Z)-flupentixol dihydrochloride
CAS51529-01-2
pharmaceutical raw material
ReferenceSame Category
Esflurbiprofen
CAS51543-39-6
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;dihydrate;hydrochloride
InChIKey
TXMZWEASFRBVKY-IOQDSZRYSA-N
SMILES
C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.O.O.Cl
Synonyms (26)
- NALOXONE HYDROCHLORIDE DIHYDRATE (EP MONOGRAPH)
- Naloxone for peak identification, European Pharmacopoeia (EP)
- Naloxone hydrochloride dihydrate, European Pharmacopoeia (EP)
- Naloxone HCl Dihydrate
- Naloxone chlorhydrate