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Home/Compounds/API/Naloxone hydrochloride
C19H22ClNO4
363.8 g/mol
APIDanger

Naloxone hydrochloride

CAS357-08-4EC206-611-0
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Naloxone hydrochloride is a hydrochloride salt form of naloxone, an opioid antagonist. It is primarily used as a pharmaceutical raw material for reversing the effects of opioids, including in the management of opioid overdose.

pharmaceutical manufacturing for opioid reversal agentsactive ingredient in opioid antagonist formulations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Naloxone hydrochloride dihydrate

CAS51481-60-8

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.79

Naloxone 3-Methyl Ether

CAS70866-64-7

research compound

SimilarStructure SimilarSimilarity 0.75

Naltrexone

CAS16590-41-3

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.75

Naltrexone hydrochloride

CAS16676-29-2

pharmaceutical raw material

ReferenceSame Category

Galantamine

CAS357-70-0

pharmaceutical raw material

ReferenceSame Category

Carboprost methyl

CAS35700-21-1

pharmaceutical raw material

ReferenceSame Category

Pemetrexed disodium heptahydrate

CAS357166-29-1

pharmaceutical raw material

ReferenceSame Category

Pemetrexed disodium hemipentahydrate

CAS357166-30-4

pharmaceutical raw material

Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
Identifiers
IUPAC Name

(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride

InChIKey

RGPDIGOSVORSAK-STHHAXOLSA-N

SMILES

C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl

Synonyms (59)
  • NLX
  • REXTOVY
  • RIVIVE
  • Naloxone Hydrochloride Injection, USP, Auto-Injector
  • Naloxone hydrochloride (JP18/USP)
  • 357-08-4 (HCl)
  • EVZIO (AUTOINJECTOR)
  • EVZIO(R) NALOXONE HCl
  • Evzio
  • Evzio (TN)
  • Hydrochloride, Naloxone
  • NALOXONE HCI
  • NARCAN NALOXONE HCI
  • Nafoxone Hydrochloride
  • Nalone
  • Nalonee
  • Naloxon hydrochloride
  • Naloxone HCl
  • Naloxone Hydrochloride Nasal
  • Naloxone hydrochloride
  • Nalxone Hydrochloride
  • Narcan
  • Narcan (TN)
  • Narcan Naloxone HCL
  • Narcan neonatal
  • Narcanti
  • Narconil
  • Prenoxad
  • Zimhi