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Home/Compounds/API/Naltrexone hydrochloride
C20H24ClNO4
377.9 g/mol
APIDanger

Naltrexone hydrochloride

CAS16676-29-2EC240-723-0
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Naltrexone hydrochloride is a pharmaceutical raw material used as an opioid receptor antagonist. It is primarily supplied for the manufacturing of medications that support the management of alcohol and opioid use disorders by reducing cravings.

pharmaceutical manufacturing for alcohol use disorder supportpharmaceutical manufacturing for opioid use disorder support

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Naltrexone

CAS16590-41-3

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.75

Naloxone hydrochloride

CAS357-08-4

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.75

Naloxone hydrochloride dihydrate

CAS51481-60-8

pharmaceutical raw material

ApplicationSame Use

10alpha-Hydroxynaloxone

CAS2139253-68-0

pharmaceutical raw material

ReferenceSame Category

Desmopressin

CAS16679-58-6

pharmaceutical raw material

ReferenceSame Category

(E/Z)-doxepin

CAS1668-19-5

pharmaceutical raw material

ReferenceSame Category

(+/-)-narwedine

CAS1668-86-6

pharmaceutical raw material

ReferenceSame Category

(-)-ivabradine

CAS167072-91-5

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H341Suspected of causing genetic defects

Customs Tariff Classification

The international HS code for Naltrexone hydrochloride (CAS 16676-29-2) is 2939.19.

HS code (international, 6-digit)

2939.19

EU CN code (8-digit)

2939 19 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride

InChIKey

RHBRMCOKKKZVRY-ITLPAZOVSA-N

SMILES

C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl

Synonyms (40)
  • XR-NTX
  • Naltrexone hydrochloride (USP)
  • Naltrexone hydrochloride, European Pharmacopoeia (EP)
  • Antaxone
  • Depade
  • EN-1639A (AS HYDROCHLORIDE)
  • En 1639A
  • Naltrel
  • Naltrexone Depot
  • Naltrexone Hcl
  • Naltrexone hydrochloride
  • Naltrexone hydrochloride CRS
  • ReVia
  • ReVia (TN)
  • Trexan
  • Trexonil
  • naltrexone monohydrochloride

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