C24H25ClFN5O3
485.9 g/mol
APIWarning
Afatinib
CAS439081-18-2EC810-720-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Afatinib is a pharmaceutical raw material used in the manufacture of certain medications. It is a tyrosine kinase inhibitor compound with a complex aromatic and heterocyclic structure, containing amide and ether functional groups.
pharmaceutical manufacturingresearch compound
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Afatinib
CAS850140-72-6
pharmaceutical raw material
StrongSame Parent
Afatinib dimaleate
CAS850140-73-7
pharmaceutical raw material
ReferenceSame Category
Elobixibat
CAS439087-18-0
pharmaceutical raw material
ReferenceSame Category
Lasmiditan
CAS439239-90-4
pharmaceutical raw material
ReferenceSame Category
Lasmiditan succinate
CAS439239-92-6
pharmaceutical raw material
ReferenceSame Category
Niflumic acid
CAS4394-00-7
pharmaceutical raw material
Referencestereoisomer of
Afatinib, (R)-
CAS945553-91-3
pharmaceutical raw material
Referencestereoisomer of
Afatinib D6
CAS1313874-96-2
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKey
ULXXDDBFHOBEHA-CWDCEQMOSA-N
SMILES
CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4
Synonyms (34)
- Afatinib (USAN/INN)
- (E/Z)-Afatinib
- (E/Z)-Afatinib (Standard)
- (S)-Afatinib
- 850140-72-6 (free base)
- AFATINIB [MART.]
- Afatinib
- Afatinib (BIBW2992)
- Afatinib - Bio-X trade mark
- Afatinib E-Isomer
- Afatinib, Free Base
- BIBW 2992
- BIBW2992 (Tovok)
- BIBW2992,Afatinib
- Tomtovok
- Tovok
- afatinibum
Sourcing Afatinib?
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