Home/Compounds/Pharmaceutical Intermediate/2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate)
C21H21ClO5
388.8 g/mol
Pharmaceutical IntermediateWarning
Hoffer's chlorosugar
CAS4330-21-6EC224-367-3
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
Hoffer's chlorosugar is a protected chlorinated sugar derivative used as an intermediate in the synthesis of nucleosides. Its structure features two 4-methylbenzoyl ester groups and a chlorine atom at the anomeric position.
intermediate for nucleoside synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 4330-21-6
Related Compounds
SimilarStructure SimilarSimilarity 0.80
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Referencestereoisomer of
1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose
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Referencesame scaffold
2-Deoxy-alpha-D-erythropentofuranose 1-acetate 3,5-bis(4-chlorobenzoate)
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Referencesame scaffold
2-Deoxy-2,2-difluoro-alpha-D-erythro-pentofuranose 3,5-dibenzoate 1-methanesulfonate
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
[(2R,3S,5R)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate
InChIKey
FJHSYOMVMMNQJQ-OTWHNJEPSA-N
SMILES
CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](C[C@H](O2)Cl)OC(=O)C3=CC=C(C=C3)C
Synonyms (18)
- Hoffer's Chlorosugar (~90%)
- Hoffer's a-chlo ro sugar
- Hoffer's chlorosugar