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Home/Compounds/Pharmaceutical Intermediate/1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose
C21H21ClO5
388.8 g/mol
Pharmaceutical IntermediateWarning

1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose

CAS3601-89-6EC800-102-2
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is an intermediate used in nucleoside synthesis, featuring a chlorinated deoxyribose backbone with two 4-methylbenzoyl protecting groups. It is a key building block for the production of modified nucleosides in pharmaceutical manufacturing.

Nucleoside synthesis intermediatePharmaceutical intermediate for modified nucleosides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 3601-89-6

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Related Compounds

SimilarStructure SimilarSimilarity 0.80

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Referencestereoisomer of

2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate)

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Referencesame scaffold

2-Deoxy-alpha-D-erythropentofuranose 1-acetate 3,5-bis(4-chlorobenzoate)

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Referencesame scaffold

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

[(2R,3S)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate

InChIKey

FJHSYOMVMMNQJQ-PAMZHZACSA-N

SMILES

CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](CC(O2)Cl)OC(=O)C3=CC=C(C=C3)C

Synonyms (11)
  • Brivudine Impurity 23
  • Hoffer's chloro sugar